Acetate-free Biofiltration for the Prevention of Intradialytic Hypеrcapnia in a Patient with Limited Pulmonary Reserve

Authors

  • Laura Di Leo Division of Nephrology, Dialysis and Renal Transplantation, A.O. Ospedale Niguarda Ca’-Granda, Milan, Italy
  • Maria Luisa Querques Division of Nephrology, Dialysis and Renal Transplantation, A.O. Ospedale Niguarda Ca’-Granda, Milan, Italy
  • Chiara Brunati Division of Nephrology, Dialysis and Renal Transplantation, A.O. Ospedale Niguarda Ca’-Granda, Milan, Italy
  • Mara Cabibbe Division of Nephrology, Dialysis and Renal Transplantation, A.O. Ospedale Niguarda Ca’-Granda, Milan, Italy
  • Alberto Menegotto Division of Nephrology, Dialysis and Renal Transplantation, A.O. Ospedale Niguarda Ca’-Granda, Milan, Italy
  • Alberto Montoli Division of Nephrology, Dialysis and Renal Transplantation, A.O. Ospedale Niguarda Ca’-Granda, Milan, Italy
  • Giacomo Colussi Division of Nephrology, Dialysis and Renal Transplantation, A.O. Ospedale Niguarda Ca’-Granda, Milan, Italy

DOI:

https://doi.org/10.22141/2307-1257.0.4.14.2015.74906

Keywords:

respiratory acidosis, hypercapnia, bicarbonate hemodialysis, acetate-free biofiltration

Abstract

A case of acute hypercapnia occurring during a session of bicarbonate hemodialysis is reported. The 82-year old female patient was affected by cardiac insufficiency, pulmonary hypertension and chronic obstructive lung disease. She developed acute symptomatic respiratory acidosis immediately after the beginning of a bicarbonate hemodialysis session, with arterial pH of 7.25 and paCO2 of 48.1 mmHg. This was related to the well known, but frequently forgotten, CO2 load from bicarbonate-based dialysate.
We treated her with acetate-free biofiltration, with stable paCO2 throughout the session. Physiopathology of blood gas dynamics during hemodialysis is reviewed.

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References

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Additional Files

Published

2022-01-19

How to Cite

Di Leo, L., Querques, M. L., Brunati, C., Cabibbe, M., Menegotto, A., Montoli, A., & Colussi, G. (2022). Acetate-free Biofiltration for the Prevention of Intradialytic Hypеrcapnia in a Patient with Limited Pulmonary Reserve. KIDNEYS, (4.14), 91–95. https://doi.org/10.22141/2307-1257.0.4.14.2015.74906

Issue

Section

Clinical Observation